Brain Research Team

Ongoing studies

The studies

What are they?

What is a study?

Clinical studies or clinical research are evaluating new strategies to identify, prevent, treat or manage disease with the aim of improving the health of people. A clinical study is research in which you freely agree to participate. Nevertheless, without the voluntary participation of people, studies cannot exist.

We focus on

We are studying the impact of aging on brain structure and on the metabolism of major fuels in the brain. Our work involves ketogenic strategies to reduce the risk and progression of cognitive decline associated with aging and Alzheimer’s disease.

Ongoing studies

Take a look

The break-ad study

The break-ad study

New ketone supplement for the brain

A ketone supplement in the form of … ketones! In recent years, new ketone supplements have started to appear on the market. Unlike TCM oils or high fat diets, ketone salts can be used directly by the body. They therefore have a potential to increase ketones even more and therefore have a more marked effect on the preservation of the brain. Indeed during aging, an energy deficit appears in the brain and providing an alternative fuel to compensate for it could help to preserve the aging brain.

The BREAK-AD study aims to confirm the effect of ketones on brain function and assess the potential of ketone salts to do so.

People in general good health, 55 years and over with slight changes in memory are sought. This 6-month study includes 12 visits including memory tests and brain scans. Contact us for more information.

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The heart-ketone study

The heart-ketone study

What's good for the heart is good for the brain ... and vice versa?

Most of the recommendations for maintaining a healthy heart, such as getting physical activity, controlling your blood pressure, and quitting smoking, are all great recommendations for maintaining a healthy brain as you age. What if the opposite is true? Ketones, the brain’s main alternative fuel, have been studied for several years as a way to compensate for the energy deficit associated with sugar observed during aging.

But the heart is also a heavy consumer of ketones, a fast and efficient source for it! The study currently underway at the Center for Research on Aging will be the first to measure the use of ketones directly by the heart, thanks to scans unique in the world. Healthy participants between the ages of 45 and 64 are sought, in order to better understand the heart’s energy use and needs. This new knowledge could eventually lead to the use of ketone supplements as a treatment to help the heart function better in certain diseases, such as heart failure or diabetes for example. Get informed!

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How to participate

Want to participate in one of our studies? Just contact us!

Contact us

FAQ

Question/answer

Why participate in a research project?

For the desire to help others with the aim of developing new or better treatments OR For the desire to take a more active role in one's own health care OR For the desire to have access to new medical treatments before they are not available.

Clinical trials cannot exist without the people who choose to take part in them.

How will my personal data be managed?

Your file is identified by a specific code and not by your name, which protects your identity. The researcher keeps the key to the code linking your name to your file. The decoding can only be done by the researcher or by a person delegated by the latter.

Do we get paid?

You will receive financial compensation for your participation. The amounts differ depending on the degree of involvement related to the project.

What is a placebo?

A placebo is a chemically inactive substance, which is given as if it was a treatment but has no therapeutic value. It’s essential in a clinical trial to verifying the efficacy of a product under study. The active product must be more effective than the placebo to find its way onto the market.

Who can participate?

Anyone aged 18 and over, with or without a health problem, may be eligible for our projects. Eligibility criteria vary between projects.

What are genetic tests?

Genes are responsible for the development and functioning of the body. Certain genes can be associated with a disease or the risk of developing it, but can also influence how our body responds to a drug or to our diet. Analyzing certain genes can therefore help us understand how the body works or explain why the effectiveness of treatment may vary from person to person.

What will my participation bring on a personal level?

There may be personal benefits associated with you participation in research projects, but we cannot guarantee this. However, the information resulting from these research projects could contribute to the advancement of knowledge in the field.

Is there any medication to take?

Currently, no drug is being evaluated in our projects.

Will I get my results?

For your safety, the results of the blood tests and certain information related to the scans will appear in your medical file. A mention of your participation in the projects will appear in your file if you are a patient of the memory clinic, but will not include any results. The examinations carried out in the projects do not make it possible to make a diagnosis or screening.

Can I end my participation at any time?

Your participation in research projects is voluntary. You can withdraw from this project at any time, without having to give any reasons. You just have to inform the research team. Your decision not to participate in or withdraw from research projects will have no impact on the quality of care and services to which you are entitled or on your relationship with the teams providing them.

What is a scan?

A scan is a medical imaging method that measures the activity of an organ in three dimensions. To do this, a harmless radioactive tracer with a know performance is used.

Are there any risks associated with the projects?

The possible side effects associated with the consumption of supplements present in our studies are mainly gastrointestinal discomfort, which is however rare, mild and transient. The risk associated with scans is mainly due to the low dose of radiation you will receive from the injection of radioactive tracers. The radiation dose received for all scans poses a risk that is considered low.