Ongoing Studies
But what is it?
Clinical trials, or clinical research, evaluate new strategies to detect, prevent, treat, or manage diseases, with the aim of improving people’s health. A clinical trial is research in which you freely choose to participate. Therefore, without the participation of volunteers, these studies could not exist.
We study the impact of aging on brain structure as well as on the metabolism of the brain’s main energy sources. Our work focuses on ketogenic strategies aimed at reducing the risk and progression of age-related cognitive decline and Alzheimer’s disease.
Discover the ongoing studies
Health, imaging, and cognition across the menopausal transition
This study aims to better understand changes in cognition and brain function during the different stages of the menopausal transition.
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Ketone supplementation in psychosis
People with psychotic disorders have twice the risk of dying from a cardiovascular event and are four times more likely to be obese than the general population. The standard treatment, antipsychotics, causes significant metabolic side effects.
However, it is important to note that patients experiencing a first episode of psychosis already show certain disruptions in glucose homeostasis, suggesting that metabolic dysregulation may be intrinsic to psychotic disorders, independent of antipsychotic effects. Thus, treatments or interventions targeting metabolism are of real interest for this population.
This is a first ketogenic intervention study that will assess the feasibility of ketone supplementation!
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Questions/Answers
Why participate in a study?
For the desire to help others in order to develop new or better treatments OR For the desire to play a more active role in one's own healthcare OR For the willingness to have access to new medical treatments before they become available.
Clinical trials cannot exist without the people who choose to take part in them.
How will my personal data be handled?
Your file is identified by a specific code and not by your name, which protects your identity. The key to the code linking your name to your file is kept by the researcher responsible for the research project. Decoding can only be done by the researcher or by a person delegated by the researcher.
Is it compensated?
You will receive financial compensation for participating in our projects. The amounts differ depending on the level of involvement related to the project.
What is a placebo?
A placebo is a chemically inactive substance that is administered as if it were a treatment but has no therapeutic value. It is essential in a clinical trial that aims to verify the effectiveness of a product under study. The active product must be more effective than the placebo to reach the market.
Who can participate?
Anyone aged 18 and over, with or without health problems, may be eligible for our projects. Eligibility criteria vary by project.
What is genetic testing?
Genes are responsible for the development and functioning of the body. Some genes may be associated with a disease or the risk of developing one, but can also influence how our body responds to a medication or our diet. Analyzing certain genes can therefore help us understand how the body works or why the effectiveness of a treatment can vary from one person to another.
What will participation bring on a personal level?
You may derive a personal benefit from your participation in research projects, but we cannot guarantee it. Furthermore, the information resulting from this research project could contribute to the advancement of knowledge in the field.
Is there medication involved?
Currently, no medication is being evaluated in our projects.
Will I receive my results?
For your safety, blood test results and certain information related to scans will appear in your medical record. A mention of your participation in the projects will appear in your file if you are a patient at the memory clinic, but will not include any results. The examinations performed in the projects do not allow for diagnosis or screening.
Can I stop at any time?
Your participation in research projects is voluntary. You can withdraw from this project at any time, without having to give reasons, by informing the research team. Your decision not to participate in research projects or to withdraw from them will have no impact on the quality of care and services to which you are entitled or on your relationship with the teams providing them.
What is a scan?
A medical imaging method that allows three-dimensional measurement of an organ's activity. To do this, a harmless radioactive tracer whose behavior is known is used.
Are there risks associated with the studies?
The possible side effects associated with consuming supplements present in our studies are mainly gastrointestinal discomfort, which is however rare, mild, and transient. The risk related to scans is mainly due to the low dose of radiation you will receive from the injection of radioactive tracers. The radiation dose received for all scans poses a risk that is considered low.
