For brain disorders
Senior Canada Research Chair in brain energy metabolism (2003-2010).
University Research Chair in brain energy metabolism (2012-2019).
350 peer-reviewed publications with 23,000 citations, an H-index of 79 and an i10-index of 286 (Google Scholar); 5 books; 2 patents.
2020 review on ketotherapeutics ranked in top 1% of all Nature Reviews Drug Discovery publications.
Elected to the French National Academy of Medicine; 5th Canadian.
Chevreul Medal, French Society for Research on Lipids (2017).
9 of his 44 students have gone on to academic appointments in Canada (4), USA (2), Europe (2) and Asia (1).
Developed the concept of ketones to rescue the ‘brain energy gap’ in Alzheimer disease.
First to demonstrate that ketones improve cognitive performance early in Alzheimer disease because they correct declining brain fuel supply.
First to assess whether a ketogenic supplement increases the benefit of exercise in Parkinson disease.
Developed the 1st method to measure brain glucose and ketone metabolism by PET imaging.
Solid track record of clinical trials testing dietary supplements that require regulatory approval.